Section: Application Domains

Tumor growth-oncology

On this topic, we want to propose branching processes to model appearance of mutations in tumor through new collaborations with clinicians. The observed process is the "circulating DNA" (ctDNA). The final purpose is to use ctDNA as a early biomarker of the resistance to an immunotherapy treatment. It is the aim of the ITMO project. Another topic is the identification of dynamic network of expression. We continue our work on low-grade gliomas. The ongoing collaboration with Montpellier CHU, and a new one with Montreal CRHUM should provide us more data. We initiate as well interactions with researchers from Montreal LIO to extend the previous work. We still have much work to do in modeling to reach our goal of a decision-aid tool for personalised medicine. In the same context, there is a question of clustering analysis of a brain cartography obtained by sensorial simulations during awake surgery.